In vivo study found anticoagulant activity for an isolated constituent. Human study in athletes administered a preparation of Siberian ginseng and andrographis found reduced coagulation

Evidence suggests this interaction might occur in some patients

Clinical evaluation by a healthcare professional is recommended to assess the degree of intervention required

Anticoagulant and antiplatelet agents

Human trials in women with breast and ovarian cancer undergoing chemotherapy treatment

Evidence suggests this interaction is likely to occur in most patients

Healthcare professional intervention unlikely to be required

Chemotherapeutic agents

Depending on drug and disease state

CYP2A1, CYP2C9, CYP2D6, and CYP3A4 substrates

In vitro , animal and human ex vivo studies

Digoxin

Hypoglycaemic drugs

Two case reports (ginseng type not specified)

Evidence suggests this interaction can occur, but is not likely to occur in many patients

Intervention by a healthcare professional may be required

Ginseng (Siberian)